platelet glycoproteins การใช้

In very high-risk scenarios, inhibitors of the platelet glycoprotein ? IIb ? 3a receptor such as eptifibatide or tirofiban may be used.
Platelet glycoprotein Ib ( GPIb ) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain.
In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene ( GP1BB; platelet glycoprotein Ib ) is used, resulting in the 3.5 kb transcript.
For example, botrocetin, found in the venom of Bothrops jararaca, activates von Willebrand factor ( vWF ) by inducing it to bind to platelet glycoprotein Ib ( GPIb ) thereby providing the surface for initial platelet aggregation.
The organization of the SELPLG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.